Targeted Isolation of Antibiotic Brominated Alkaloids from the Marine Sponge <em>Pseudoceratina durissima</em> Using Virtual Screening and Molecular Networking

Targeted Isolation of Antibiotic Brominated Alkaloids from the Marine Sponge <em>Pseudoceratina durissima</em> Using Virtual Screening and Molecular Networking

Many targeted natural product isolation approaches rely on the use of pre-existing bioactivity information to inform the strategy used for the isolation of new bioactive compounds. Bioactivity information can be available either in the form of prior assay data or via Structure Activity Relationship...

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Bibliographic Details
Main Authors: James Lever, Florian Kreuder, Jason Henry, Andrew Hung, Pierre-Marie Allard, Robert Brkljača, Colin Rix, Aya C. Taki, Robin B. Gasser, Jan Kaslin, Donald Wlodkowic, Jean-Luc Wolfender, Sylvia Urban
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Marine Drugs
Subjects:
MRSA pathogen
virtual screening
in silico molecular docking
targeted anti-biotic isolation
zebrafish
cheminformatic analysis
Online Access:https://www.mdpi.com/1660-3397/20/9/554

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https://www.mdpi.com/1660-3397/20/9/554

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