Enhanced oleate uptake and lipotoxicity associated with laurate

Free fatty acids have been reported to induce cell death (lipotoxicity), but the effects depend on the carbon chain length and number of double bonds. Medium‐chain saturated fatty acids (MC‐SFAs), such as laurate, have less lipotoxicity than long‐chain saturated fatty acids (LC‐SFAs), such as palmit...

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Bibliographic Details
Main Authors: Yasuyuki Kitaura, Kana Inoue, Naoki Kato, Nahomi Matsushita, Yoshiharu Shimomura
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1016/j.fob.2015.05.008