Novel Method for Quantifying AhR-Ligand Binding Affinities Using Microscale Thermophoresis

Novel Method for Quantifying AhR-Ligand Binding Affinities Using Microscale Thermophoresis

The aryl hydrocarbon receptor (AhR) is a highly conserved cellular sensor of a variety of environmental pollutants and dietary-, cell- and microbiota-derived metabolites with important roles in fundamental biological processes. Deregulation of the AhR pathway is implicated in several diseases, inclu...

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Bibliographic Details
Main Authors: Anne Stinn, Jens Furkert, Stefan H. E. Kaufmann, Pedro Moura-Alves, Michael Kolbe
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biosensors
Subjects:
AhR
recombinant expression
ligand binding
MST
high-throughput screening
Online Access:https://www.mdpi.com/2079-6374/11/3/60

Internet

https://www.mdpi.com/2079-6374/11/3/60

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