Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer's disease.

Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer's disease.

Blood-brain barrier (BBB) dysfunction may be involved in the increased sensitivity of Alzheimer's disease (AD) patients to antipsychotics, including amisulpride. Studies indicate that antipsychotics interact with facilitated glucose transporters (GLUT), including GLUT1, and that GLUT1 BBB expre...

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Bibliographic Details
Main Authors: Sevda T Boyanova, Ethlyn Lloyd-Morris, Christopher Corpe, Khondaker Miraz Rahman, Doaa B Farag, Lee K Page, Hao Wang, Alice L Fleckney, Ariana Gatt, Claire Troakes, Gema Vizcay-Barrena, Roland Fleck, Suzanne J Reeves, Sarah A Thomas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0286278&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0286278&type=printable

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