POLQ immunostaining behaves as a prognostic factor for pancreatic carcinoma

POLQ immunostaining behaves as a prognostic factor for pancreatic carcinoma

BackgroundDNA polymerase theta (POLQ) is a translesion synthesis polymerase essential for the repair of double strand breaks by the error-prone TMEJ (Theta Mediated End Joining) pathway. Although POLQ participates in maintaining genome stability, several studies have shown that its overexpression co...

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Bibliographic Details
Main Authors: Laura del Puerto-Nevado, María J. Fernández-Aceñero, Arancha Cebrián, Yuliia Fatych, Luis I. Díez-Valladares, Elia Pérez-Aguirre, Sofía de la Serna, Alejandra García-Botella, Javier Martínez-Useros, Jesús García-Foncillas, Pedro A. Mateos-Gómez
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Oncology
Subjects:
POLQ
pancreatic carcinoma
immunostaining
overall survival
prognostic factor
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1433179/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2024.1433179/full

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