Combined treatment of xenon and hypothermia in newborn rats--additive or synergistic effect?

Breathing the inert gas Xenon (Xe) enhances hypothermic (HT) neuroprotection after hypoxia-ischemia (HI) in small and large newborn animal models. The underlying mechanism of the enhancement is not yet fully understood, but the combined effect of Xe and HT could either be synergistic (larger than th...

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Bibliographic Details
Main Authors: Hemmen Sabir, Lars Walløe, John Dingley, Elisa Smit, Xun Liu, Marianne Thoresen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4186877?pdf=render