Clinicopathological significance of p16, cyclin D1, Rb and MIB-1 levels in skull base chordoma and chondrosarcoma

Objective: To investigate the expression of p16, cyclin D1, retinoblastoma tumor suppressor protein (Rb) and MIB-1 in skull base chordoma and chondrosarcoma tissues, and to determine the clinicopathological significance of the above indexes in these diseases. Methods: A total of 100 skull base chord...

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Bibliographic Details
Main Authors: Jun-qi Liu, Qiu-hang Zhang, Zhen-lin Wang
Format: Article
Language:English
Published: Wiley 2015-09-01
Series:World Journal of Otorhinolaryngology-Head and Neck Surgery
Online Access:http://www.sciencedirect.com/science/article/pii/S2095881115300159