The Wnt/β-catenin signaling pathway affects the distribution of cytoskeletal proteins in Aβ treated PC12 cells

Alzheimer’s disease is pathologically characterized by the presence of senile plaques and neurofibrillary tangles in the central nervous system. Amyloid β-protein is toxic to neurons and induces phosphorylation of Tau protein, which accumulates in paired helical filaments and leads to the formation...

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Bibliographic Details
Main Author: Zhifeng Tian, Xiaoling Zhang, Zhijun Zhao, Fuhua Zhang, Tongxing Deng
Format: Article
Language:English
Published: IMR Press 2019-09-01
Series:Journal of Integrative Neuroscience
Subjects:
Online Access:https://jin.imrpress.com/fileup/1757-448X/PDF/1569287163310-1171757868.pdf