Peptides Derived from Type IV Collagen, CXC Chemokines, and Thrombospondin-1 Domain-Containing Proteins Inhibit Neovascularization and Suppress Tumor Growth in MDA-MB-231 Breast Cancer Xenografts

Angiogenesis or neovascularization, the process of new blood vessel formation from preexisting microvasculature, involves interactions among several cell types including parenchymal, endothelial cells, and immune cells. The formation of new vessels is tightly regulated by a balance between endogenou...

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Bibliographic Details
Main Authors: Jacob E. Koskimaki, Emmanouil D. Karagiannis, Elena V. Rosca, Farhad Vesuna, Paul T. Winnard, Jr, Venu Raman, Zaver M. Bhujwalla, Aleksander S. Popel
Format: Article
Language:English
Published: Elsevier 2009-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558609800973