Finding small molecular compounds to decrease trimethylamine oxide levels in atherosclerosis by virtual screening

The intestinal microbial metabolite trimethylamine oxide (TMAO) affects the formation and development of atherosclerosis (AS). The design and development of an effective targeted drug to reduce serum TMAO levels may provide new avenues for inhibiting AS morbidity. Target genes that may elevate TMAO...

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Bibliographic Details
Main Authors: Luo Jiaxin, Zhang Aoqi, Yao Yuan, Yuan Jun
Format: Article
Language:English
Published: De Gruyter 2023-10-01
Series:Open Chemistry
Subjects:
Online Access:https://doi.org/10.1515/chem-2023-0128