Identification and characterization of miRNAs in spleens of sheep subjected to repetitive vaccination

Abstract Accumulative evidence has shown that short non-coding RNAs such as miRNAs can regulate the innate and adaptive immune responses. Aluminium hydroxide is a commonly used adjuvant in human and veterinary vaccines. Despite its extended use, its mechanism of action is not fully understood and ve...

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Bibliographic Details
Main Authors: Endika Varela-Martínez, Martin Bilbao-Arribas, Naiara Abendaño, Javier Asín, Marta Pérez, Lluís Luján, Begoña M. Jugo
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32603-7