Synthetic route optimization of Sumepirin antiepileptic drug candidate

Synthetic route optimization of Sumepirin antiepileptic drug candidate

In this work we describe the transformation of synthetic route of the antiepileptic drug candidate Sumepirin starting from discovery stage. Initial method included six step process requiring two steps of purification using colon chromatography and has poor overall yield of target compound. The proce...

Full description

Bibliographic Details
Main Authors: M. S. Dzyurkevich, N. V. Shtyrlin, Y. G. Shtyrlin
Format: Article
Language:English
Published: Uralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina 2020-12-01
Series:Chimica Techno Acta
Subjects:
pyridoxine
synthetic route optimization
scale-up
purification
antiepileptic drug
technology
Online Access:https://journals.urfu.ru/index.php/chimtech/article/view/4802

Internet

https://journals.urfu.ru/index.php/chimtech/article/view/4802

Similar Items