SARS-CoV-2 mRNA Dual Immunization Induces Innate Transcriptional Signatures, Establishes T-Cell Memory and Coordinates the Recall Response

SARS-CoV-2 mRNA Dual Immunization Induces Innate Transcriptional Signatures, Establishes T-Cell Memory and Coordinates the Recall Response

Background: mRNA vaccines have played a crucial role in controlling the SARS-CoV-2 global pandemic. However, the immunological mechanisms involved in the induction, magnitude and longevity of mRNA-vaccine-induced protective immunity are still unclear. Methods: In our study, we used whole-RNA sequenc...

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Bibliographic Details
Main Authors: Ioanna Papadatou, Maria Geropeppa, Kleio-Maria Verrou, Marianna Tzanoudaki, Theano Lagousi, Emmanouil Liatsis, Vana Spoulou
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Vaccines
Subjects:
SARS-CoV-2 vaccine
immunological memory
transcriptomics
systems vaccinology
Online Access:https://www.mdpi.com/2076-393X/11/1/103

Internet

https://www.mdpi.com/2076-393X/11/1/103

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