Protocol for computationally evaluating the loss of stoichiometry and coordinated expression of proteins

Summary: Dysregulation of the transcriptional or translational machinery can alter the stoichiometry of multiprotein complexes and occurs in natural processes such as aging. Loss of stoichiometry has been shown to alter protein complex functions. We provide a protocol and associated code that use om...

Full description

Bibliographic Details
Main Authors: Stefan Hinz, Michael E. Todhunter, Mark A. LaBarge
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722000624