Administration of Mycobacterium leprae rHsp65 aggravates experimental autoimmune uveitis in mice.

Administration of Mycobacterium leprae rHsp65 aggravates experimental autoimmune uveitis in mice.

The 60 kDa heat shock protein family, Hsp60, constitutes an abundant and highly conserved class of molecules that are highly expressed in chronic-inflammatory and autoimmune processes. Experimental autoimmune uveitis [EAU] is a T cell mediated intraocular inflammatory disease that resembles human uv...

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Bibliographic Details
Main Authors: Eliana B Marengo, Alessandra Gonçalves Commodaro, Jean Pierre S Peron, Luciana V de Moraes, Fernanda C V Portaro, Rubens Belfort, Luiz Vicente Rizzo, Osvaldo Augusto Sant'Anna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2775913?pdf=render

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http://europepmc.org/articles/PMC2775913?pdf=render

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