Diabetic beta-cells can achieve self-protection against oxidative stress through an adaptive up-regulation of their antioxidant defenses.

Diabetic beta-cells can achieve self-protection against oxidative stress through an adaptive up-regulation of their antioxidant defenses.

BACKGROUND:Oxidative stress (OS), through excessive and/or chronic reactive oxygen species (ROS), is a mediator of diabetes-related damages in various tissues including pancreatic beta-cells. Here, we have evaluated islet OS status and beta-cell response to ROS using the GK/Par rat as a model of typ...

Full description

Bibliographic Details
Main Authors: Grégory Lacraz, Florence Figeac, Jamileh Movassat, Nadim Kassis, Josiane Coulaud, Anne Galinier, Corinne Leloup, Danielle Bailbé, Françoise Homo-Delarche, Bernard Portha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2715861?pdf=render

Internet

http://europepmc.org/articles/PMC2715861?pdf=render

Similar Items