Sodium formononetin-3'-sulphonate alleviates cerebral ischemia–reperfusion injury in rats via suppressing endoplasmic reticulum stress-mediated apoptosis

Sodium formononetin-3'-sulphonate alleviates cerebral ischemia–reperfusion injury in rats via suppressing endoplasmic reticulum stress-mediated apoptosis

Abstract Background Sodium formononetin-3ʹ-sulphonate (Sul-F) may alleviate I/R injury in vivo with uncertain mechanism. Endoplasmic reticulum (ER) stress-mediated apoptosis participates in the process of cerebral ischemia‐reperfusion (I/R) injury. Our aim is to figure out the effect of Sul-F on cer...

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Bibliographic Details
Main Authors: Yue Bai, Zhiwei He, Weisong Duan, He Gu, Kefeng Wu, Wei Yuan, Wenkang Liu, Huaipeng Huang, Yanan Li
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Neuroscience
Subjects:
Formononetin
Cerebral ischemia-reperfusion injury
Endoplasmic reticulum stress
Cell apoptosis
Ischemic penumbra
Stroke
Online Access:https://doi.org/10.1186/s12868-022-00762-4

Internet

https://doi.org/10.1186/s12868-022-00762-4

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