CCDC85A is regulated by miR-224-3p and augments cancer cell resistance to endoplasmic reticulum stress

CCDC85A is regulated by miR-224-3p and augments cancer cell resistance to endoplasmic reticulum stress

MicroRNAs (miRNAs) play pivotal roles in the tumor microenvironment. Here, we analyzed miRNAs in tumor stromal fibroblasts. Expression of miR-224-3p in cancer-associated fibroblasts (CAF) from scirrhous gastric cancer patients was lower than in normal fibroblasts (NF). Introduction of a miR-224-3p m...

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Bibliographic Details
Main Authors: So Takahashi, Kurara Takagane, Go Itoh, Sei Kuriyama, Michinobu Umakoshi, Akiteru Goto, Kazuyoshi Yanagihara, Masakazu Yashiro, Katsunori Iijima, Masamitsu Tanaka
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Oncology
Subjects:
CCDC85A
miR224-3p
exosomes
ER stress
cisplatin resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1196546/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1196546/full

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