The role of dysregulated ghrelin/LEAP-2 balance in anorexia nervosa

Summary: LEAP-2 is a ghrelin antagonist with an anorexigenic drive. This study investigates the evolution of plasma ghrelin and LEAP-2 concentrations in 29 patients with anorexia nervosa (AN) before and after refeeding and compares it to physiological adaptations during fasting in healthy controls o...

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Bibliographic Details
Main Authors: Chloé Tezenas du Montcel, Philibert Duriez, Jingxian Cao, Nicolas Lebrun, Nicolas Ramoz, Odile Viltart, Philip Gorwood, Virginie Tolle
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223020734