Relevance of 2′-O-Methylation and Pseudouridylation for the Malignant Melanoma

Relevance of 2′-O-Methylation and Pseudouridylation for the Malignant Melanoma

The two RNA modifications 2′-O-methylation and pseudouridylation occur on several RNA species including ribosomal RNAs leading to an increased translation as well as cell proliferation associated with distinct functions. Using malignant melanoma (MM) as a model system the proteins mediating these RN...

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Bibliographic Details
Main Authors: Simon Jasinski-Bergner, Juliane Blümke, Claudia Wickenhauser, Barbara Seliger
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
snoRNA
2′-O-methylation
pseudouridylation
microRNA
malignant melanoma
Online Access:https://www.mdpi.com/2072-6694/13/5/1167

Internet

https://www.mdpi.com/2072-6694/13/5/1167

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