Unmasking the Warburg Effect: Unleashing the Power of Enzyme Inhibitors for Cancer Therapy

The Warburg effect (or aerobic glycolysis), which was first described in 1926 by Otto Heinrich Warburg, consists of the change in glucose metabolism in cancer cells. In normal cells, glucose metabolism finalizes in the mitochondria through oxidative phosphorylation (OXPHOS) in the presence of oxygen...

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Bibliographic Details
Main Authors: Eduardo Angulo-Elizari, Leire Gaviria-Soteras, Irati Zubiri, Sandra Ramos-Inza, Carmen Sanmartin, Daniel Plano
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Drugs and Drug Candidates
Subjects:
Online Access:https://www.mdpi.com/2813-2998/2/3/37