Unmasking the Warburg Effect: Unleashing the Power of Enzyme Inhibitors for Cancer Therapy
The Warburg effect (or aerobic glycolysis), which was first described in 1926 by Otto Heinrich Warburg, consists of the change in glucose metabolism in cancer cells. In normal cells, glucose metabolism finalizes in the mitochondria through oxidative phosphorylation (OXPHOS) in the presence of oxygen...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-09-01
|
Series: | Drugs and Drug Candidates |
Subjects: | |
Online Access: | https://www.mdpi.com/2813-2998/2/3/37 |