Approach to Pyrido[2,1-<i>b</i>][1,3]benzothiazol-1-ones via In Situ Generation of Acyl(1,3-benzothiazol-2-yl)ketenes by Thermolysis of Pyrrolo[2,1-<i>c</i>][1,4]benzothiazine-1,2,4-triones

Approach to Pyrido[2,1-<i>b</i>][1,3]benzothiazol-1-ones via In Situ Generation of Acyl(1,3-benzothiazol-2-yl)ketenes by Thermolysis of Pyrrolo[2,1-<i>c</i>][1,4]benzothiazine-1,2,4-triones

Acyl(imidoyl)ketenes are highly reactive heterocumulenes that enable diversity-oriented synthesis of various drug-like heterocycles. Such ketenes, bearing heterocyclic substituents, afford angularly fused pyridin-2(1<i>H</i>)-ones in their [4+2]-cyclodimerization reactions. We have utili...

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Bibliographic Details
Main Authors: Ekaterina A. Lystsova, Alexander S. Novikov, Maksim V. Dmitriev, Andrey N. Maslivets, Ekaterina E. Khramtsova
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Molecules
Subjects:
acyl(imidoyl)ketene
cycloaddition
DFT calculations
heterocumulene
hetero-Diels–Alder reaction
thermolysis
Online Access:https://www.mdpi.com/1420-3049/28/14/5495

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https://www.mdpi.com/1420-3049/28/14/5495

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