SeMet alleviates AFB1-induced oxidative stress and apoptosis in rabbit kidney by regulating Nrf2//Keap1/NQO1 and PI3K/AKT signaling pathways

SeMet alleviates AFB1-induced oxidative stress and apoptosis in rabbit kidney by regulating Nrf2//Keap1/NQO1 and PI3K/AKT signaling pathways

The purpose of this study was to explore the protective effect of SeMet on renal injury induced by AFB1 in rabbits and its molecular mechanism. Forty rabbits of 35 days old were randomly divided into control group, AFB1 group (0.3 mg AFB1/kg b.w), 0.2 mg/kg Se + AFB1 group (0.3 mg AFB1/kg b.w + 0.2 ...

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Bibliographic Details
Main Authors: Yumei Liu, Jianing Wang, Zhaoyang Chang, Shuangjun Li, Zhikai Zhang, Shiyang Liu, Shuaishuai Wang, Lan Wei, Qiongxia Lv, Ke Ding, Ziqiang Zhang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Mycotoxin
SeMet
Oxidative stress
Tissue damage
Nrf2/Keap1/NQO1
PI3K/AKT
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323012460

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http://www.sciencedirect.com/science/article/pii/S0147651323012460

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