New Conotoxin SO-3 Targeting N-type Voltage-Sensitive Calcium Channels

Selective blockers of the N-type voltage-sensitive calcium (CaV) channels are useful in the management of severe chronic pain. Here, the structure and function characteristics of a novel N-type CaV channel blocker, SO-3, are reviewed. SO-3 is a 25-amino acid conopeptide originally derived from the v...

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Bibliographic Details
Main Authors: Lei Wen, Sheng Yang, Wenxia Zhou, Peitang Huang, Yongxiang Zhang
Format: Article
Language:English
Published: MDPI AG 2006-04-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/4/3/215/