A Novel Constitutional t(3;8)(p26;q21) and <i>ANKRD26</i> and <i>SRP72</i> Variants in a Child with Myelodysplastic Neoplasm: Clinical Implications

A Novel Constitutional t(3;8)(p26;q21) and <i>ANKRD26</i> and <i>SRP72</i> Variants in a Child with Myelodysplastic Neoplasm: Clinical Implications

Background: Childhood myelodysplastic neoplasm (cMDS) often raises concerns about an underlying germline predisposition, and its verification is necessary to guide therapeutic choice and allow family counseling. Here, we report a novel constitutional t(3;8)(p26;q21) in a child with MDS, inherited fr...

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Bibliographic Details
Main Authors: Viviane Lamim Lovatel, Ana Paula Bueno, Elaiza Almeida Antônio de Kós, Laura Guimarães Corrêa Meyer, Gerson Moura Ferreira, Mayara de Fátima Kalonji, Fabiana Vieira de Mello, Cristiane Bedran Milito, Elaine Sobral da Costa, Eliana Abdelhay, Maria Dolores Tabernero Redondo, Maria S. Pombo-de-Oliveira, Teresa de Souza Fernandez
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Journal of Clinical Medicine
Subjects:
childhood myelodysplastic neoplasm
constitutional cytogenetic abnormality
genetic variants
Online Access:https://www.mdpi.com/2077-0383/12/9/3171

Internet

https://www.mdpi.com/2077-0383/12/9/3171

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