The impact of genetic manipulation of laminin and integrins at the blood–brain barrier

Abstract Blood vessels in the central nervous system (CNS) are unique in having high electrical resistance and low permeability, which creates a selective barrier protecting sensitive neural cells within the CNS from potentially harmful components in the blood. The molecular basis of this blood–brai...

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Bibliographic Details
Main Authors: Sebok K. Halder, Arjun Sapkota, Richard Milner
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-022-00346-8