Interaction of Arylidenechromanone/Flavanone Derivatives with Biological Macromolecules Studied as Human Serum Albumin Binding, Cytotoxic Effect, Biocompatibility Towards Red Blood Cells

Interaction of Arylidenechromanone/Flavanone Derivatives with Biological Macromolecules Studied as Human Serum Albumin Binding, Cytotoxic Effect, Biocompatibility Towards Red Blood Cells

The aim of this study was to determine the cytotoxic effect of 3-arylidenechromanone (<b>1</b>) and 3-arylideneflavanone (<b>2</b>) on HL-60 and NALM-6 cell lines (two human leukemia cell lines) and a WM-115 melanoma cell line. Both compounds exhibited high cytotoxic activity...

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Bibliographic Details
Main Authors: Angelika A. Adamus-Grabicka, Magdalena Markowicz-Piasecka, Michał B. Ponczek, Joachim Kusz, Magdalena Małecka, Urszula Krajewska, Elzbieta Budzisz
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
synthesis
crystal structure
cytotoxic effect
benzoflavanone/chromanone derivatives
erythrotoxicity
Online Access:https://www.mdpi.com/1420-3049/23/12/3172

Internet

https://www.mdpi.com/1420-3049/23/12/3172

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