Real world data on young patients with high-risk diffuse large B-cell lymphoma treated with R-CHOP or R-CHOEP - MYC, BCL2 and BCL6 as prognostic biomarkers.

Double expression of MYC and BCL2 proteins (DE) and double-hit MYC+BCL2/BCL6 translocations (DH) were established as important biomarkers in patients with diffuse large B-cell lymphoma (DLBCL) by the 2016 revision of the World Health Organization classification of lymphoid neoplasms. Whether this ap...

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Main Authors: Mette Ølgod Pedersen, Anne Ortved Gang, Peter Brown, Michael Pedersen, Helle Knudsen, Signe Ledou Nielsen, Tim Poulsen, Tobias Wirenfeldt Klausen, Estrid Høgdall, Peter Nørgaard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5663399?pdf=render