Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial

Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial

Abstract Background Postpartum haemorrhage (PPH) is responsible for about 100,000 maternal deaths every year, most of which occur in low- and middle-income countries. Tranexamic acid (TXA) reduces bleeding by inhibiting the enzymatic breakdown of fibrin blood clots. TXA decreases blood loss in surge...

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Bibliographic Details
Main Authors: Katharine Ker, Ian Roberts, Rizwana Chaudhri, Bukola Fawole, Danielle Beaumont, Eni Balogun, Danielle Prowse, Tracey Pepple, Kiran Javaid, Aasia Kayani, Sabaratnam Arulkumaran, Imelda Bates, Haleema Shakur-Still, on behalf of the WOMAN-2 trial collaborators
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Trials
Subjects:
Antifibrinolytic
Clinical trial
Tranexamic acid
Postpartum haemorrhage
Maternal anaemia
Online Access:http://link.springer.com/article/10.1186/s13063-018-3081-x

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http://link.springer.com/article/10.1186/s13063-018-3081-x

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