Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses.

Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses.

Neonates are highly susceptible to infectious diseases and defective antiviral pDC immune responses have been proposed to contribute to this phenomenon. Isolated cord blood pDCs innately responded to a variety of TLR7 and TLR9 dependent viruses, including influenza A virus (IAV), human immunodeficie...

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Bibliographic Details
Main Authors: Xiaoming Zhang, Alice Lepelley, Elie Azria, Pierre Lebon, Gwenaelle Roguet, Olivier Schwartz, Odile Launay, Claude Leclerc, Richard Lo-Man
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3542339?pdf=render

Internet

http://europepmc.org/articles/PMC3542339?pdf=render

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