Light-mediated double-strand DNA cleavage by an alkyldicobalamin
Agents that cause double-strand breaks (DSBs) of DNA via radical formation have been demonstrated to be effective in treating cancer because DSBs result in cellular apoptosis. Light-responsive agents for the treatment of cancer have been of interest for decades because they afford the ability to spa...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | Journal of Photochemistry and Photobiology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666469023000507 |