Overcoming limitations in current measures of drug response may enable AI-driven precision oncology

Abstract Machine learning (ML) models of drug sensitivity prediction are becoming increasingly popular in precision oncology. Here, we identify a fundamental limitation in standard measures of drug sensitivity that hinders the development of personalized prediction models – they focus on absolute ef...

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Bibliographic Details
Main Authors: Katja Ovchinnikova, Jannis Born, Panagiotis Chouvardas, Marianna Rapsomaniki, Marianna Kruithof-de Julio
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-024-00583-0