Overcoming limitations in current measures of drug response may enable AI-driven precision oncology
Abstract Machine learning (ML) models of drug sensitivity prediction are becoming increasingly popular in precision oncology. Here, we identify a fundamental limitation in standard measures of drug sensitivity that hinders the development of personalized prediction models – they focus on absolute ef...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-04-01
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Series: | npj Precision Oncology |
Online Access: | https://doi.org/10.1038/s41698-024-00583-0 |