Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition

Transcriptional mechanism of IRF8 and PU.1 governs microglial activation in neurodegenerative condition

ABSTRACT Microglial activation occurs in divergent neuropathological conditions. Such microglial event has the key involvement in the progression of CNS diseases. However, the transcriptional mechanism governing microglial activation remains poorly understood. Here, we investigate the microglial res...

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Bibliographic Details
Main Authors: Nan Zhou, Kaili Liu, Yue Sun, Ying Cao, Jing Yang
Format: Article
Language:English
Published: Oxford University Press 2018-11-01
Series:Protein & Cell
Subjects:
microglia
3D fluorescence imaging technique
neurodegeneration
IRF8
PU.1
Online Access:http://link.springer.com/article/10.1007/s13238-018-0599-3

Internet

http://link.springer.com/article/10.1007/s13238-018-0599-3

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