MTHFD2 promotes ovarian cancer growth and metastasis via activation of the STAT3 signaling pathway

MTHFD2 promotes ovarian cancer growth and metastasis via activation of the STAT3 signaling pathway

Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) is a bifunctional enzyme located in the mitochondria. MTHFD2 has been reported to be overexpressed in several malignant tumors and is implicated in cancer development. This study aimed to investigate the effect of MTHFD2 on ovarian cancer progressio...

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Bibliographic Details
Main Authors: Qiutong Li, Fang Yang, Xiu Shi, Shimin Bian, Fangrong Shen, Yuhong Wu, Chenjie Zhu, Fengqing Fu, Juan Wang, Jinhua Zhou, Youguo Chen
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:FEBS Open Bio
Subjects:
cell cycle
EMT progress
methylenetetrahydrofolate dehydrogenase 2
ovarian cancer
STAT3 signaling pathway
Online Access:https://doi.org/10.1002/2211-5463.13249

Internet

https://doi.org/10.1002/2211-5463.13249

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