Lyplal1 is dispensable for normal fat deposition in mice

Lyplal1 is dispensable for normal fat deposition in mice

Genome-wide association studies (GWAS) have detected association between variants in or near the Lysophospholipase-like 1 (LYPLAL1) locus and metabolic traits, including central obesity, fatty liver and waist-to-hip ratio. LYPLAL1 is also known to be upregulated in the adipose tissue of obese patien...

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Bibliographic Details
Main Authors: Rachel A. Watson, Amy S. Gates, Elizabeth H. Wynn, Fiona E. Calvert, Amandine Girousse, Christopher J. Lelliott, Inês Barroso
Format: Article
Language:English
Published: The Company of Biologists 2017-12-01
Series:Disease Models & Mechanisms
Subjects:
Adipose tissue
Genome-wide association study
Lyplal1
Model organism
Mouse
Obesity
Online Access:http://dmm.biologists.org/content/10/12/1481

Internet

http://dmm.biologists.org/content/10/12/1481

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