Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a

Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a

Abstract Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and...

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Bibliographic Details
Main Authors: Yonggan Sun, Qixing Nie, Shanshan Zhang, Huijun He, Sheng Zuo, Chunhua Chen, Jingrui Yang, Haihong Chen, Jielun Hu, Song Li, Jiaobo Cheng, Baojie Zhang, Zhitian Zheng, Shijie Pan, Ping Huang, Lu Lian, Shaoping Nie
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43622-3

Internet

https://doi.org/10.1038/s41467-023-43622-3

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