Binding mechanism of full-length Aβ40 peptide to a mixed lipid bilayer

The destructive effect of Aβ peptides on membranes is an important source of its cytotoxicity in the pathogenesis of Alzheimer’s disease. We have investigated the binding mechanism between the Aβ42 peptide and bilayer in our former work. However, as another abundant form of Aβ peptides in the physio...

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Bibliographic Details
Main Authors: Ke Wang, Wensheng Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2024.1367793/full