FLU-v, a Broad-Spectrum Influenza Vaccine, Induces Cross-Reactive Cellular Immune Responses in Humans Measured by Dual IFN-γ and Granzyme B ELISpot Assay

Previous reports demonstrated that FLU-v, a peptide-based broad-spectrum influenza vaccine candidate, induced antibody and cellular immune responses in humans. Here, we evaluate cellular effector functions and cross-reactivity. PBMC sampled pre- (day 0) and post-vaccination (days 42 and 180) from va...

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Bibliographic Details
Main Authors: Fredrik Oftung, Lisbeth M. Næss, Ida Laake, Gregory Stoloff, Olga Pleguezuelos
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/9/1528