Bovine Mucosal Heparins Are Comparable to Porcine Mucosal Heparin at USP Potency Adjusted Levels

Bovine Mucosal Heparins Are Comparable to Porcine Mucosal Heparin at USP Potency Adjusted Levels

Introduction: Bovine mucosal heparins (BMH) are currently being developed for re-introduction for both medical and surgical indications. BMH active pharmaceutical ingredient (API) exhibits a somewhat weaker USP potency when compared to PMHs. We hypothesized that when dosages are normalized based on...

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Bibliographic Details
Main Authors: Walter Jeske, Ahmed Kouta, Ambar Farooqui, Fakiha Siddiqui, Varun Rangnekar, Manoj Niverthi, Rajan Laddu, Debra Hoppensteadt, Omer Iqbal, Jeanine Walenga, Jawed Fareed
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Medicine
Subjects:
heparin
potency
bovine
porcine
pharmacokinetics
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2018.00360/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2018.00360/full

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