Engineering a modular 44Ti/44Sc generator: eluate evaluation in preclinical models and estimation of human radiation dosimetry

Engineering a modular 44Ti/44Sc generator: eluate evaluation in preclinical models and estimation of human radiation dosimetry

Abstract Background 44Sc/47Sc is an attractive theranostic pair for targeted in vivo positron emission tomographic (PET) imaging and beta-particle treatment of cancer. The 44Ti/44Sc generator allows daily onsite production of this diagnostic isotope, which may provide an attractive alternative for P...

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Bibliographic Details
Main Authors: Nadia Benabdallah, Hanwen Zhang, Ryan Unnerstall, Amanda Fears, Lucy Summer, Michael Fassbender, Buck E. Rodgers, Diane Abou, Valery Radchenko, Daniel L. J. Thorek
Format: Article
Language:English
Published: SpringerOpen 2023-02-01
Series:EJNMMI Research
Subjects:
Isotope generator
Positron emission tomography
Scandium-44
Pharmacokinetics
Online Access:https://doi.org/10.1186/s13550-023-00968-5

Internet

https://doi.org/10.1186/s13550-023-00968-5

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