Engineering a modular 44Ti/44Sc generator: eluate evaluation in preclinical models and estimation of human radiation dosimetry
Abstract Background 44Sc/47Sc is an attractive theranostic pair for targeted in vivo positron emission tomographic (PET) imaging and beta-particle treatment of cancer. The 44Ti/44Sc generator allows daily onsite production of this diagnostic isotope, which may provide an attractive alternative for P...
Main Authors: | Nadia Benabdallah, Hanwen Zhang, Ryan Unnerstall, Amanda Fears, Lucy Summer, Michael Fassbender, Buck E. Rodgers, Diane Abou, Valery Radchenko, Daniel L. J. Thorek |
---|---|
Format: | Article |
Language: | English |
Published: |
SpringerOpen
2023-02-01
|
Series: | EJNMMI Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13550-023-00968-5 |
Similar Items
-
Developments toward the Implementation of <sup>44</sup>Sc Production at a Medical Cyclotron
by: Nicholas P. van der Meulen, et al.
Published: (2020-10-01) -
Synthesis, Physicochemical, Labeling and In Vivo Characterization of <sup>44</sup>Sc-Labeled DO3AM-NI as a Hypoxia-Sensitive PET Probe
by: Dániel Szücs, et al.
Published: (2022-05-01) -
Separation of <sup>44</sup>Sc from <sup>44</sup>Ti in the Context of A Generator System for Radiopharmaceutical Purposes with the Example of [<sup>44</sup>Sc]Sc-PSMA-617 and [<sup>44</sup>Sc]Sc-PSMA-I&T Synthesis
by: Anton A. Larenkov, et al.
Published: (2021-10-01) -
Cyclotron production of 43Sc and 44gSc from enriched 42CaO, 43CaO, and 44CaO targets
by: Kaelyn V. Becker, et al.
Published: (2023-04-01) -
FP Shell Effective Interactions and Nuclear Shell Structure of 44Sc
by: Maryam K. Hassan, et al.
Published: (2023-03-01)