Secretin Receptor as a Target in Gastrointestinal Cancer: Expression Analysis and Ligand Development

Secretin was originally discovered as a gastrointestinal peptide that stimulates fluid secretion from the pancreas and liver and delays gastric emptying. In disease, a secretin receptor (SCTR) was found to occur as a splice variant in gastrinoma and pancreatic adenocarcinoma. Overexpression of SCTR...

Полное описание

Библиографические подробности
Главные авторы: Anja Klussmeier, Stefan Aurich, Lars Niederstadt, Bertram Wiedenmann, Carsten Grötzinger
Формат: Статья
Язык:English
Опубликовано: MDPI AG 2022-02-01
Серии:Biomedicines
Предметы:
Online-ссылка:https://www.mdpi.com/2227-9059/10/3/536