5-aminolevulinic acid, fluorescein sodium, and indocyanine green for glioma margin detection: analysis of operating wide-field and confocal microscopy in glioma models of various grades

IntroductionSurgical resection remains the first-line treatment for gliomas. Several fluorescent dyes are currently in use to augment intraoperative tumor visualization, but information on their comparative effectiveness is lacking. We performed systematic assessment of fluorescein sodium (FNa), 5-a...

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Main Authors: Evgenii Belykh, Liudmila Bardonova, Irakliy Abramov, Vadim A. Byvaltsev, Talgat Kerymbayev, Kwanha Yu, Debbie R. Healey, Ernesto Luna-Melendez, Benjamin Deneen, Shwetal Mehta, James K. Liu, Mark C. Preul
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1156812/full