Epigenetic regulation of BAF60A determines efficiency of miniature swine iPSC generation

Abstract Miniature pigs are an ideal animal model for translational research to evaluate stem cell therapies and regenerative applications. While the derivation of induced pluripotent stem cells (iPSCs) from miniature pigs has been demonstrated, there is still a lack of a reliable method to generate...

Full description

Bibliographic Details
Main Authors: Hongli Jiao, Ming-Song Lee, Athillesh Sivapatham, Ellen M. Leiferman, Wan-Ju Li
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12919-6