Clostridium perfringens Sialidases: Potential Contributors to Intestinal Pathogenesis and Therapeutic Targets

Clostridium perfringens is a major cause of histotoxic and intestinal infections of humans and other animals. This Gram-positive anaerobic bacterium can produce up to three sialidases named NanH, NanI, and NanJ. The role of sialidases in histotoxic infections, such as gas gangrene (clostridial myone...

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Bibliographic Details
Main Authors: Jihong Li, Francisco A. Uzal, Bruce A. McClane
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/8/11/341