Growth deficits in cystic fibrosis mice begin in utero prior to IGF-1 reduction.

Growth deficits in cystic fibrosis mice begin in utero prior to IGF-1 reduction.

Growth deficits are common in cystic fibrosis (CF), but their cause is complex, with contributions from exocrine pancreatic insufficiency, pulmonary complications, gastrointestinal obstructions, and endocrine abnormalities. The CF mouse model displays similar growth impairment despite exocrine pancr...

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Bibliographic Details
Main Authors: Rebecca Darrah, Ilya Bederman, Megan Vitko, Dana M Valerio, Mitchell L Drumm, Craig A Hodges
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5383306?pdf=render

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http://europepmc.org/articles/PMC5383306?pdf=render

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