The association of circulating amylin with β‐amyloid in familial Alzheimer's disease

The association of circulating amylin with β‐amyloid in familial Alzheimer's disease

Abstract Introduction This study assessed the hypothesis that circulating human amylin (amyloid‐forming) cross‐seeds with amyloid beta (Aβ) in early Alzheimer's disease (AD). Methods Evidence of amylin‐AD pathology interaction was tested in brains of 31 familial AD mutation carriers and 20 cogn...

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Bibliographic Details
Main Authors: Han Ly, Nirmal Verma, Savita Sharma, Deepak Kotiya, Sanda Despa, Erin L. Abner, Peter T. Nelson, Gregory A. Jicha, Donna M. Wilcock, Larry B. Goldstein, Rita Guerreiro, José Brás, Angela J. Hanson, Suzanne Craft, Andrew J. Murray, Geert Jan Biessels, Claire Troakes, Henrik Zetterberg, John Hardy, Tammaryn Lashley, AESG, Florin Despa
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
amylin
amyloid
familial Alzheimer's disease
islet amyloid polypeptide
sporadic Alzheimer's disease
Online Access:https://doi.org/10.1002/trc2.12130

Internet

https://doi.org/10.1002/trc2.12130

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