Modeling the compaction of bacterial chromosomes by biomolecular crowding and the cross-linking protein H-NS

Abstract Cells orchestrate the action of various molecules toward organizing their chromosomes. Using a coarse-grained computational model, we study the compaction of bacterial chromosomes by the cross-linking protein H-NS and cellular crowders. In this work, H-NS, modeled as a mobile “binder,” can...

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Bibliographic Details
Main Authors: Youngkyun Jung, Amir Sadeghi, Bae-Yeun Ha
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50355-2