Optimizing the Clinical Impact of CAR-T Cell Therapy in B-Cell Acute Lymphoblastic Leukemia: Looking Back While Moving Forward

Optimizing the Clinical Impact of CAR-T Cell Therapy in B-Cell Acute Lymphoblastic Leukemia: Looking Back While Moving Forward

Chimeric antigen receptor T-cell (CAR-T) therapy has been successful in creating extraordinary clinical outcomes in the treatment of hematologic malignancies including relapsed or refractory (R/R) B-cell acute lymphoblastic leukemia (B-ALL). With several FDA approvals, CAR-T therapy is recognized as...

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Bibliographic Details
Main Authors: Pouya Safarzadeh Kozani, Pooria Safarzadeh Kozani, Fatemeh Rahbarizadeh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
chimeric antigen receptor
cytokine release syndrome
neurotoxicity
acute lymphoblastic leukemia
adoptive cell therapy
cancer immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.765097/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.765097/full

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