Impact of pH modification of the empirically used tobramycin ophthalmic solution on MIC90 concentration in tears and aqueous humor of donkeys (Equus asinus)

Impact of pH modification of the empirically used tobramycin ophthalmic solution on MIC90 concentration in tears and aqueous humor of donkeys (Equus asinus)

Abstract Background Commercial tobramycin ophthalmic solution is frequently used empirically to treat ocular disorders in equines, despite being primarily formulated for use in humans. It has been noted that tobramycin MIC90 concentration (minimal inhibitory concentration to 90% of microbial growth)...

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Bibliographic Details
Main Authors: Ahmed Ibrahim, Mohamed A. A. Abd-Elrasoul, Mahmoud S. Sabra
Format: Article
Language:English
Published: BMC 2024-05-01
Series:BMC Veterinary Research
Subjects:
Keratitis
Topical antibiotics
Tobramycin
Drug bioavailability
Equines
Eyes
Online Access:https://doi.org/10.1186/s12917-024-04072-1

Internet

https://doi.org/10.1186/s12917-024-04072-1

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